Research with Impact is a series of articles that shine the spotlight on recently published studies with an HHS Researcher as lead author. Each piece features a study published in a journal with an Impact Factor greater than 10 and provides information about the author and the research they lead. If their work strikes a cord with you, Tweet us at @HamHealthSc and include #HHSResearch!
Dr. Sanjit Jolly MD, MSc, FRCP is an interventional cardiologist at Hamilton Health Sciences and associate professor at McMaster University. He has formal training in clinical trials, with an MSc in Health Research Methodology from McMaster University. Dr. Jolly is presently involved in postgraduate medical training of residents and fellows in invasive angiography, angioplasty, general cardiology, and internal medicine.
Dr. Jolly was Principle Investigator on a study that was published in the Lancet. The study is entitled: Outcomes after Thrombus Aspiration for ST elevation Myocardial Infarction: 1 year follow-up of the prospective randomised TOTAL Trial. 2016 Jan 9;387(10014):127-35 ( http://dx.doi.org/10.1016/S0140-6736(15)00448-1 ).
Two large trials have reported contradictory results at 1 year after thrombus aspiration in ST elevation myocardial infarction (STEMI). In a 1-year follow-up of the largest randomised trial of thrombus aspiration, the aim was to clarify the longer-term benefits, to help guide clinical practice.
Interpretation: Routine thrombus aspiration during PCI for STEMI did not reduce longer-term clinical outcomes and might be associated with an increase in stroke. As a result, thrombus aspiration can no longer be recommended as a routine strategy in STEMI.