A series of articles has been created by HHS Research which shine the spotlight on studies published in 2014 with an HHS Researcher as lead author. Each piece features a study published in a journal with an Impact Factor greater than 10 and provides information about the author and about the research they lead. If their work strikes a cord with you, Tweet us at @HamHealthSc and include #HHSResearch.
Dr. Martin O’Donnell MB MRCPI is Associate Clinical Professor, Divisions of General Internal Medicine and Hematology and Thromboembolism, Department of Medicine at McMaster University. His research interests include: research in evidence-based medicine and vascular disease, particularly in the areas of stroke and venous thrombosis.
O’Donnell, M., Mente, A., Koon, T., Yusuf, S. (2014). Urinary sodium and potassium excretion, mortality and cardiovascular events, New England Journal of Medicine, 371, 612-632.
Background of study: The optimal range of sodium intake for cardiovascular health is controversial.
Conclusions: In this study, in which sodium intake was estimated based on measured urinary excretion, an estimated sodium intake between 3 g per day and 6 g per day was associated with a lower risk of death and cardiovascular events than was either a higher or lower estimated level of intake. As compared with estimated potassium excretion that was less than 1.50 g per day, higher potassium excretion was associated with a lower risk of death and cardiovascular events.