A series of articles has been created by HHS Research which shine the spotlight on studies published in 2014 with an HHS Researcher as lead author. Each piece features a study published in a journal with an Impact Factor greater than 10 and provides information about the author and about the research they lead. If their work strikes a cord with you, Tweet us at @HamHealthSc and include hashtag: HHSResearch
Dr. Andrew Mente received his MA at York University and his doctoral degree in Epidemiology from the University of Toronto. He completed his post-doctoral training in cardiovascular epidemiology at McMaster University, and is currently an Associate Professor in Clinical Epidemiology and Biostatistics at McMaster University. Dr. Mente is a member of the Population Genomics Program and is a Principal Investigator for the Epidemiology program at the Population Health Research Institute. Dr. Mente is interested in examining novel gene variants and their interaction with dietary components and patterns associated with cardiovascular disease outcomes (e.g., myocardial infarction, sudden cardiac death, heart failure, and stroke) and key intermediate phenotypes (e.g., dysglycemia, dyslipidemia, abdominal obesity, and hypertension). He has published 45 papers and two Chapters.
Mente, A., O’Donnell, M., Koon, T. & Yusuf, S. (2014) Association of urinary sodium and potassium excretion with blood pressure. New England Journal of Medicine, 370, 601-611.
Background of study: Higher levels of sodium intake are reported to be associated with higher blood pressure. Whether this relationship varies according to levels of sodium or potassium intake and in different populations is unknown.
Conclusions: In this study, the association of sodium and potassium intake, as determined from measurements of excretion of these cations, with blood pressure was nonlinear and most pronounced in persons consuming high-sodium diets, persons with hypertension, and older persons.